Browsing by Author "Barry-Holson, Keegan"
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Hematopoietic stem cell quiescence promotes error-prone dna repair and mutagenesis
Mohrin, Mary; Bourke, Emer; Alexander, David; Warr, Matthew R.; Barry-Holson, Keegan; Le Beau, Michelle M.; Morrison, Ciaran G.; Passegué, Emmanuelle (Elsevier BV, 2010-08-01)Most adult stem cells, including hematopoietic stem cells (HSCs), are maintained in a quiescent or resting state in vivo. Quiescence is widely considered to be an essential protective mechanism for stem cells that minimizes ...