Browsing by Title
Now showing items 771-790 of 14646
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Amyotrophic lateral sclerosis patient ipsc-derived astrocytes impair autophagy via non-cell autonomous mechanisms
(Springer Nature, 2017-06-13)Amyotrophic lateral sclerosis, a devastating neurodegenerative disease, is characterized by the progressive loss of motor neurons and the accumulation of misfolded protein aggregates. The latter suggests impaired proteostasis ... -
An abnormal but functionally active complement component c9 protein found in an irish family with subtotal c9 deficiency
(Wiley-Blackwell, 2003-03-01)Two independently segregating C9 genetic defects have previously been reported in two siblings in an Irish family with subtotal C9 deficiency. One defect would lead to an abnormal C9 protein, with replacement of a cysteine ... -
An algebraic derivation of a certain exact sequence
(Elsevier BV, 1989-11-01) -
An analysis of non-observance of best practice in a software measurement program
(Elsevier BV, 2012-01-01) -
An analysis of open innovation practices in the medical technology sector in ireland
(Elsevier BV, 2015-01-01) -
An analysis of the impact of playout delay adjustments introduced by voip jitter buffers on listening speech quality
(S. Hirzel Verlag, 2015-05-01)This paper investigates the impact of frequent and small playout delay adjustments (time-shifting) of 30 ms or less introduced to silence periods by Voice over IP (VoIP) jitter buffer strategies on listening quality perceived ... -
An analysis of the impact on trends in automation on human error potential in brachytherapy
(Elsevier BV, 2015-01-01) -
An analytical method for predicting the geometrical and optical properties of the human lens under accommodation
(The Optical Society, 2014-04-28) -
An assessment of bird species within irish agricultural landscapes using the field boundary evaluation and grading system
(Informa UK Limited, 2010-01-01)Capsule The Field Boundary Evaluation and Grading System (FBEGS) is a useful predictor of bird populations found in field boundaries located in southeast Ireland. Aims To assess the potential of FBEGS to evaluate the ... -
An assessment of histological margins and recurrence of melanoma in situ
(Ovid Technologies (Wolters Kluwer Health), 2015-02-01)Background: Melanoma in situ (MIS) accounts for up to 27% of all melanomas. MIS has no metastatic potential and the aim should be to excise the lesion completely with a clear histological margin, although margin clearance ... -
An assessment of pseudo-operational ground-based light detection and ranging sensors to determine the boundary-layer structure in the coastal atmosphere
(Hindawi Limited, 2012-01-01)Twenty-one cases of boundary-layer structure were retrieved by three co-located remote sensors, One LIDAR and two ceilometers at the coastal site of Mace Head, Ireland. Data were collected during the ICOS field campaign ... -
An assessment of rna content inprymnesium parvum,prymnesium polylepis,cf.chattonellasp. andkarlodinium veneficumunder varying environmental conditions for calibrating an rna microarray for species detection
(Oxford University Press (OUP), 2014-02-03)Traditional methods of identification and enumeration can be somewhat ambiguous when identifying phytoplankton that requires electron microscopic examination to verify specific morphological features. Members of the genus ... -
An assessment of stress in irish interns
(Informa UK Limited, 2012-03-27) -
An assessment of the surface ozone trend in ireland relevant to air pollution and environmental protection
(Elsevier BV, 2012-07-01)Hourly data (1994-2009) of surface ozone concentrations at eight monitoring sites have been investigated to assess target level and long-term objective exceedances and their trends. The European Union (EU) ozone target ... -
An atr‐dependent function for the ddx19 rna helicase in nuclear r‐loop metabolism
(EMBO, 2017-03-17)Coordination between transcription and replication is crucial in the maintenance of genome integrity. Disturbance of these processes leads to accumulation of aberrant DNA: RNA hybrids (R-loops) that, if unresolved, generate ... -
An automated system for epilepsy detection using eeg brain signals based on deep learning approach
(Elsevier BV, 2018-04-01) -
An ecosystem-based approach and management framework for the integrated evaluation of bivalve aquaculture impacts
(Inter-Research Science Center, 2012-05-08)An ecosystem-based approach to bivalve aquaculture management is a strategy for the integration of aquaculture within the wider ecosystem, including human aspects, in such a way that it promotes sustainable development, ... -
An efficient, non-viral dendritic vector for gene delivery in tissue engineering
(Springer Nature, 2017-07-19)Recent developments within the field of tissue engineering (TE) have shown that biomaterial scaffold systems can be augmented via the incorporation of gene therapeutics. The objective of this study was to assess the potential ...