Browsing by Title
Now showing items 587-606 of 14643
-
Advanced spectroscopy and APBS modeling for determination of the role of His190 and Trp103 in mouse thymidylate synthase interaction with selected dUMP analogues
(MDPI, 2021-03-06)A homo-dimeric enzyme, thymidylate synthase (TS), has been a long-standing molecular target in chemotherapy. To further elucidate properties and interactions with ligands of wild-type mouse thymidylate synthase (mTS) and ... -
Advanced therapies in pancreatic islet transplantation for type 1 diabetes mellitus
(NUI Galway, 2023-03-14)Type 1 diabetes mellitus is an autoimmune condition whereby β-cells are destroyed by the immune system causing the lack/absence of insulin production and resultant hyperglycaemia. Pancreatic islet transplantation is ... -
Advancements and challenges in multidomain multicargo delivery vehicles
(Wiley, 2018-02-15)Reparative and regenerative processes are well‐orchestrated temporal and spatial events that are governed by multiple cells, molecules, signaling pathways, and interactions thereof. Yet again, currently available ... -
Advancements in structural and functional imaging using Fourier domain optical coherence tomography
(NUI Galway, 2020-07-29)Optical Coherence Tomography (OCT) is a non-invasive optical imaging modality based on low coherence interferometry that enables high resolution, cross sectional imaging in biological tissues and materials. One major ... -
Advances in Automated Image Categorization: Sorting Images using Person Recognition Techniques
(2007-06-01)The core problem addressed by this thesis is to provide practical tools for automatic sorting and cataloging of a typical consumer collection of digital images. The thesis presents a complete system solution, comprising ... -
Advances in characterization of size-resolved organic matter in marine aerosol over the north atlantic
(Wiley-Blackwell, 2004-01-01)Size-segregated marine aerosols were collected at Mace Head Atmospheric Research Station (Ireland) during spring and autumn 2002 corresponding with the phytoplankton bloom periods in the North Atlantic. Strict control of ... -
Advances in eco-efficient agriculture: the plant-soil mycobiome
(MDPI AG, 2017-02-15)In order to achieve a desirable ecological and sustainable agriculture a thorough understanding of the plant-soil mycobiome is imperative. Commercial industrial agriculture alters greenhouse gas emissions, promotes loss ... -
Advances in evolutionary neural networks with applications in energy systems and the environment
(NUI Galway, 2018-08-29)Evolutionary neural networks combine two of the most powerful areas of computing, evolutionary algorithms and neural networks. There are a number of benefits of using evolutionary algorithms to train a network over traditional ... -
Advances in mesenchymal stem cell-mediated gene therapy for cancer
(Springer Nature, 2010-01-01)Mesenchymal stem cells have a natural tropism for tumours and their metastases, and are also considered immunoprivileged. This remarkable combination of properties has formed the basis for many studies investigating their ... -
Advances in precision medicine: tailoring individualized therapies
(MDPI AG, 2017-10-25)The traditional bench-to-bedside pipeline involves using model systems and patient samples to provide insights into pathways deregulated in cancer. This discovery reveals new biomarkers and therapeutic targets, ultimately ... -
Advances in rapid compression machine studies of low- and intermediate-temperature autoignition phenomena
(Elsevier, 2017-07-10)Rapid compression machines (RCMs) are widely used to acquire experimental insights into fuel autoignition and pollutant formation chemistry, especially at conditions relevant to current and future combustion technologies. ... -
Advances in ruthenium-based light harvesting materials and photocatalysis: From molecular photosensitizers to photoactive frameworks
(NUI Galway, 2022-04-08)The presented manuscript deals with the areas of light harvesting and photocatalysis in solar chemistry. The work presented is divided into several sections, beginning with an introductory chapter on the main topics involved ... -
Advances in stent-mediated gene delivery
(Informa Healthcare, 2016-02-16) -
Advances in the detection & repair of flash-eye defects in digital images - a review of recent patents
(Bentham Science, 2012)Red-eye and flash-eye defects in still photography continue to cause problems for digital imaging devices. New variants of flash-eye defects have appeared as cameras and cameras sub-systems get smaller in size. This paper ... -
Advances in the estimation of the reproduction number from compartmental models using contemporary Monte Carlo methods
(NUI Galway, 2024-03-08)The reproduction number represents the average number of secondary cases generated by a primary case. If the population is completely susceptible, it is referred to as the basic reproduction number (<0) and theoretically ... -
Advances in the management and treatment algorithms for anterior shoulder instability
(NUI Galway, 2022-04-28)Anterior shoulder instability is a common clinical problem, with a reported incidence ranging from 8 to 25 per 100,000 person years in the general population, with higher rates seen 1-3 in athletic populations. However, ... -
Advances in the Modelling of Facial Sub-Regions and Facial Expressions using Active Appearance Techniques
(2009-05-01)Advances are presented in the modeling of facial sub-regions, in the use of enhanced whole face-models, and based on these sub-region models, in the determination of facial expressions. Models are derived using techniques ... -
Advances in the testing of stereo image acquisition devices
(2014-01-04)The core problem addressed in the current thesis is to provide a novel test bed for depth map generation and stereo image-based algorithms. The test bed comprises of elements such as (i) the choice and calibration of ... -
Advances in Understanding, Mining, and Using People-Tags
(2012-05-31)People-tagging involves the process of adding non-hierarchical metadata to users of a system. Such metadata facilitates organising contacts and building user profiles in a collaborative fashion. People-tag-based user ... -
Advancing clinical research by semantically interconnecting aggregated medical data information in a secure context
(Springer Verlag, 2017-03-22)Electronic Health Records (EHRs) contain an increasing wealth of medical information. When combined with molecular level data, they enhance the understanding of the underlying biological mechanisms of diseases, enabling ...