dc.contributor.author | Lord, Philip | |
dc.contributor.author | Spiering, Rachel | |
dc.contributor.author | Aguillon, Juan C. | |
dc.contributor.author | Anderson, Amy E. | |
dc.contributor.author | Appel, Silke | |
dc.contributor.author | Benitez-Ribas, Daniel | |
dc.contributor.author | ten Brinke, Anja | |
dc.contributor.author | Broere, Femke | |
dc.contributor.author | Cools, Nathalie | |
dc.contributor.author | Cuturi, María Cristina | |
dc.contributor.author | Diboll, Julie | |
dc.contributor.author | Geissler, Edward | |
dc.contributor.author | Giannoukakis, Nick | |
dc.contributor.author | Gregori, Silvia | |
dc.contributor.author | van Ham, Sija Marieke | |
dc.contributor.author | Lattimer, Staci | |
dc.contributor.author | Marshall, Lindsay F. | |
dc.contributor.author | Harry, Rachel A. | |
dc.contributor.author | Hutchinson, James A. | |
dc.contributor.author | Isaacs, John D. | |
dc.contributor.author | Joosten, Irma | |
dc.contributor.author | van Kooten, Cees | |
dc.contributor.author | de Cerio, Ascensión López Díaz | |
dc.contributor.author | Nikolic, Tatjana | |
dc.contributor.author | Oral, Haluk Barbaros | |
dc.contributor.author | Sofronic-Milosavljevic, Ljiljana | |
dc.contributor.author | Ritter, Thomas | |
dc.contributor.author | Riquelme, Paloma | |
dc.contributor.author | Thomson, Angus W. | |
dc.contributor.author | Trucco, Massimo | |
dc.contributor.author | Vives-Pi, Marta | |
dc.contributor.author | Martinez-Caceres, Eva M. | |
dc.contributor.author | Hilkens, Catharien M.U. | |
dc.date.accessioned | 2017-03-27T10:20:23Z | |
dc.date.available | 2017-03-27T10:20:23Z | |
dc.date.issued | 2016-08-30 | |
dc.identifier.citation | Lord P, Spiering R, Aguillon JC, Anderson AE, Appel S, Benitez-Ribas D, ten Brinke A, Broere F, Cools N, Cuturi MC, Diboll J, Geissler EK, Giannoukakis N, Gregori S, van Ham SM, Lattimer S, Marshall L, Harry RA, Hutchinson JA, Isaacs JD, Joosten I, van Kooten C, Lopez Diaz de Cerio A, Nikolic T, Oral HB, Sofronic-Milosavljevic L, Ritter T, Riquelme P, Thomson AW, Trucco M, Vives-Pi M, Martinez-Caceres EM, Hilkens CMU. (2016) Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies. PeerJ 4:e2300 https://doi.org/10.7717/peerj.2300 | en_IE |
dc.identifier.issn | 2167-8359 | |
dc.identifier.uri | http://hdl.handle.net/10379/6408 | |
dc.description.abstract | Cellular therapies, with tolerogenic antigen-presenting cells (tolAPC) show great promise for the treatment of autoimmune diseases and for the prevention of destructive immune responses after transplantation The methodologies for generating tolAPC vary greatly between different laboratories, making it difficult to compare data from different studies; thus constituting a major hurdle for the development of standardised tolAPC therapeutic products. Here we describe an initiative by members of the tolAPC field to generate a minimum information model for tolAPC (MITAP), providing a reporting framework that will make differences and similarities between tolAPC products transparent. In this way, MITAP constitutes a first but important step towards the production of standardised and reproducible tolAPC for clinical application. | en_IE |
dc.description.sponsorship | This work was supported by a grant from the European Cooperation in Science and Technology (COST) for the AFACTT project (Action to Focus and Accelerate Cell-based Tolerance-inducing Therapies; BM1305). COST is part of the EU Framework Programme Horizon 2020. | en_IE |
dc.format | application/pdf | en_IE |
dc.language.iso | en | en_IE |
dc.publisher | PeerJ | en_IE |
dc.relation.ispartof | Peerj | en |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Ireland | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/3.0/ie/ | |
dc.subject | Cell therapy | en_IE |
dc.subject | Minimum information model | en_IE |
dc.subject | Antigen-presenting cells | en_IE |
dc.subject | Autoimmune disease | en_IE |
dc.subject | Transplantation | en_IE |
dc.subject | Tolerogenic dendritic cells | en_IE |
dc.subject | Regulatory macrophages | en_IE |
dc.subject | Reporting guidelines | en_IE |
dc.subject | Dendritic cells | en_IE |
dc.subject | Disease | en_IE |
dc.title | Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies | en_IE |
dc.type | Article | en_IE |
dc.date.updated | 2017-03-27T09:00:40Z | |
dc.identifier.doi | 10.7717/peerj.2300 | |
dc.local.publishedsource | https://doi.org/10.7717/peerj.2300 | en_IE |
dc.description.peer-reviewed | peer-reviewed | |
dc.contributor.funder | |~| | |
dc.internal.rssid | 11533000 | |
dc.local.contact | Thomas Ritter, School Of Medicine, Regenerative Medicine Institute, Biosciences, Dangan. 5329 Email: thomas.ritter@nuigalway.ie | |
dc.local.copyrightchecked | No | |
dc.local.version | ACCEPTED | |
nui.item.downloads | 378 | |