dc.contributor.author | Newland, Ben | en |
dc.contributor.author | Tai, Hongyun | en |
dc.contributor.author | Zheng, Yu | en |
dc.contributor.author | Velasco, Diego | en |
dc.contributor.author | Di Luca, Andrea | en |
dc.contributor.author | Howdle, Steven M. | en |
dc.contributor.author | Alexander, Cameron | en |
dc.contributor.author | Wang, Wenxin | en |
dc.contributor.author | Pandit, Abhay | en |
dc.date.accessioned | 2010-10-14T09:36:46Z | en |
dc.date.available | 2010-10-14T09:36:46Z | en |
dc.date.issued | 2010-06 | en |
dc.identifier.citation | Newland, B., Tai, H., Zheng, Y., Velasco, D., Di Luca, A., Howdle, S. M., et al. A highly effective gene delivery vector - hyperbranched poly(2-(dimethylamino)ethyl methacrylate) from in situ deactivation enhanced ATRP. Chemical Communications, 46(26), 4698-4700. | en |
dc.identifier.issn | 1359-7345 | en |
dc.identifier.uri | http://hdl.handle.net/10379/1340 | en |
dc.description.abstract | A hyperbranched 2-(dimethylamino)ethyl methacrylate (DMAEMA) based polymer has been synthesised by a one-pot in situ deactivation enhanced atom transfer radical polymerisation (DE-ATRP); it exhibits much higher transfection ability than linear poly(DMAEMA) and is comparable to the well known branched poly(ethylene imine) (PEI) and the SuperFect dendrimer but with lower cytotoxicity. | en |
dc.format | application/pdf | en |
dc.publisher | The Royal Society of Chemistry | en |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Ireland | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/3.0/ie/ | |
dc.subject | Gene delivery | en |
dc.subject | Network of Excellence for Functional Biomaterials | en |
dc.title | A Highly Effective Gene Delivery Vector | en |
dc.type | Article | en |
dc.local.publishedsource | http://dx.doi.org/10.1039/C0CC00439A | en |
dc.description.peer-reviewed | peer-reviewed | en |
nui.item.downloads | 765 | |